The Cancer Therapy & Research Center (CTRC) at the University of Texas Health Science Center at San Antonio requests $ 200,000 per year in developmental funds, 9.7% of the overall direct Cancer Center Support Grant (CCSG) request that will be used for: Pilot research funding to CTRC members each year. Funds($150,000/year) will be awarded following competitive RFAs. Additional pilots will be funded using CTRC funds. Funding ($50,000 per year), for start-up packages for high priority new faculty recruitment The remainder of these start-up packages will be leveraged with CTRC and institutional funds.